Margaret Talbot reports on the opioid epidemic in West Virginia. There, the overdose rate is the highest in the United States and many are fighting to help loved ones, friends, neighbors, and sometimes complete strangers get healthy. Among several sources, she profiles an emergency paramedic who routinely sees to multiple overdoses a day (sometimes the same people on repeat). A team of moms called “The Hope Dealers” drives addicts hours away to get the treatment they need. A 71-year-old doctor offers free public classes on how to administer a drug called Narcan which reverses the effects of overdoses that have become commonplace. All this in an opioid epidemic fuelled by cheap highs and small-town despair over limited prospects.