Search Results for: cancer

The Social Life of Genes

Longreads Pick

How our environment, our sense of support, and our feelings of loneliness can activate or turn off specific genes in our bodies that affect things like how we fight or heal wounds. An examination of the “social science of genetics”:

“Scientists have known for decades that genes can vary their level of activity, as if controlled by dimmer switches. Most cells in your body contain every one of your 22,000 or so genes. But in any given cell at any given time, only a tiny percentage of those genes is active, sending out chemical messages that affect the activity of the cell. This variable gene activity, called gene expression, is how your body does most of its work.

“Sometimes these turns of the dimmer switch correspond to basic biological events, as when you develop tissues in the womb, enter puberty, or stop growing. At other times gene activity cranks up or spins down in response to changes in your environment. Thus certain genes switch on to fight infection or heal your wounds—or, running amok, give you cancer or burn your brain with fever. Changes in gene expression can make you thin, fat, or strikingly different from your supposedly identical twin. When it comes down to it, really, genes don’t make you who you are. Gene expression does. And gene expression varies depending on the life you live.”

Published: Sep 3, 2013
Length: 24 minutes (6,182 words)

Reading List: One in Seven Billion

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Emily Perper is word-writing human for hire. She blogs about her favorite longreads at Diet Coker.

The student journalist, the Afghani mother, the elderly custodian, the Chinese orphan boy: each of these pieces forces the reader to stop and consider the extraordinary stories of seemingly ordinary people.

1. “At 99, A St. Petersburg Man Finds Meaning in the Working Life.” (Lane DeGregory, Tampa Bay Times, July 2013)

Feature writing wizard DeGregory has found an incredible subject: the wonderful Mr. Newton, who has worked for over 84 years and hasn’t stopped yet.

2. “‘See You on the Other Side.’” (Sara Morrison, Columbia Journalism Review, May 2013)

Jessica Lum, photojournalist, understood the empathetic necessity of storytelling. She practiced her art until she died of cancer at age 25.

3. “Matthew.” (Andrew Yellis, May 2013)

“We met when I was 15 and he was 7. Matthew was always ‘my little brother in China’ … But how can I pretend to really know what it was like to grow up in the situation he did?” Yellis tries to raise a troubled Chinese teen at his parents’ orphanage.

4. “The View from the Sitting Room.” (Angie Chuang, Vela Magazine, July 2013)

Delving into the daily lives of Afghani women, Chuang meets Amina, whose steadfastness saw her family through war, changing regimes and the disappearance of her youngest brother at the hands of KGB soldiers.

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Photo by Andrew Yellis

Longreads Guest Pick: Rustin Dodd on 'The Courage Of Jill Costello'

Rustin Dodd is a sports reporter at The Kansas City Star. For the most part, he spends his time covering Kansas basketball and football, but he has also covered the Kansas City Royals for the last five years. He’s covered two Final Fours, two Major-League All-Star Games and The Masters. He resides in Lawrence, Kan., home of the best local music scene in the Midwest.


Every year or so, I find myself going back and reading ‘The Courage of Jill Costello,’ a Sports Illustrated story by Chris Ballard from Nov. 29, 2010. It’s often said that the best sports stories are not about sports — and that’s true, of course. But this story is an example of simple, rich storytelling, elegant and beautiful. Jill Costello is a coxswain on the Cal rowing team, diagnosed with cancer before her senior season. (Ballard retraces her final year on campus, letting his deep reporting do the work.) And at its core, Costello’s story is about youth and heart and determination and time, and the question we all ask ourselves: What would we would do if we only had a little bit of life left?

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Reading List: 21 Outstanding Stories from Women's Magazines and Websites

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Are women’s magazines avoiding “serious journalism”? Guess it all depends on who’s deciding what’s serious.

The New Republic asks that question in a new article, and our biggest problem with this debate (and, to be honest, the term “longform journalism”) is that it can often run everything through a male-skewed filter of what counts as “serious journalism.” We’ve seen serious storytelling in both.

The other problem is that we’re still relying on National Magazine Awards and print-only publishers to reflect the zeitgeist. I’ve mentioned that 65% of all #longreads started out in print, but we also should spotlight the work of online publishers who are pursuing in-depth storytelling.

So, here’s a start: 21 stories from women’s magazines and sites that we’ve featured on Longreads. On Twitter, Rebecca Traister is curating some of her favorite serious work. And we’d love for you to add your favorite women’s magazine stories in the comments.

Allure

The F Word, Jennifer Weiner

Marie Claire

The Big Business of Breast Cancer, Lea Goldman

Tiger Beatdown

The Percentages: A Biography of Class, Sady Doyle

O, The Oprah Magazine

‘I Will Never Know Why’, Susan Klebold

‘We Thought the Sun Would Always Shine on Our Lives’, Paige Williams

Promises of an Unwed Father, Ta-Nehisi Coates

Is Ecstasy a Viable Treatment for Post-Traumatic Stress Disorder?, Jessica Winter

Rookie

Higher Learning, Staff

XO Jane

How A Gun-loving West Texas Girl Learned to Fear Assault Weapons, Haley B. Elkins

It Happened To Me: My Parents Adopted a Murderer, Amity Bitzel

More

How I Lost $500,000 for Love, Aryn Kyle

Vogue

Notes on a Scandal: Jenny Sanford Vogue Interview, Rebecca Johnson

Sheryl Sandberg: What She Saw at the Revolution, Kevin Conley

Susan Rice: She’s Got Game, Jonathan Van Meter

Elle

I’m For Sale, Genevieve Smith

The Hairpin

My Brother, My Mother, and a Call Girl, Mara Cohen Marks

He’s So Unusual, Jane Marie

A Goodbye to Ambien in Dubai, Amy Schumer

The Evolution of Ape-Face Johnson, Carolita Johnson

Glamour

Relationship Violence: The Secret That Kills 4 Women a Day, Liz Brody

Jezebel

What Can a Civilian Possibly Say to a Wounded Soldier?, Chloe Angyal

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Share your picks in the comments

Behind the Longreads: Antonia Crane on 'Yellow,' Our Latest Member Pick

(photo by teejayfaust, Flickr)

This week’s Member Pick is “Yellow,” a story by Antonia Crane about the days following the death of her mother. The piece will be featured in Black Clock #17 this summer and is adapted from her forthcoming book Spent. We asked her to tell us how the story first came together:

“‘Yellow’ actually began as a love letter to Cheryl Strayed’s essay ‘The Love of My Life’ (The Sun, Issue #430) which begins ‘The first time I cheated on my husband, my mother had been dead for exactly one week.’ I had become fixated on that essay because in it, Strayed’s palpable sorrow contained a sexually reckless rhythm that I related to as a dancer and sex worker. My own mother died of cancer two months into grad school and I was raging with grief. At that time, I quit my half-assed personal assistant jobs and chose to sit in the dark for two years at ‘Pleasures.’

“A lifelong dancer and athlete, I was more comfortable hurling my body at the world than eating or buying toothpaste. I remember that I could go strip or meet a client for money, but I could not remember to pick up toothpaste no matter how many times I wrote in on my hand with a black Sharpie. I came home one afternoon to a Walgreens bag on my doorknob with Crest in it and bawled.

“Strayed’s essay modeled the utensils I sought to stir up my own concoction of rage and loss that was tearing at my skin. I’m grateful she allowed me to cook in her kitchen. I was mourning my mother. I was dancing; and I wrote like a motherfucker.”

Read an excerpt of “Yellow.”

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Nora Ephron’s Final Act

Longreads Pick

Nora Ephron’s son Jacob on his mother’s last days, and the play she was working on that helped her understand her own sickness and impending death:

“In the play my mother wrote, there’s a scene toward the end, in which McAlary, sick with cancer, goes to the Poconos to visit his friend Jim Dwyer, then a columnist at The Daily News. It’s a glorious summer day, and McAlary’s 12-year-old son, Ryan, wants to do a flip off the diving board, but he gets scared and can’t do it. So McAlary takes off his shirt, walks to the edge of the diving board and says to him: ‘When you do these things, you can’t be nervous. If you think about what can go wrong, if you think about the belly flop, that’s what’ll happen.’

“And then McAlary does the flip himself and makes a perfect landing.

“It’s a metaphor, obviously, for his view about life. And I’ve come to think it might as well have been about my mother. The point is that you don’t let fear invade your psyche. Because then you might as well be dead.”

Published: Mar 6, 2013
Length: 22 minutes (5,681 words)

Manti Te’o’s Dead Girlfriend, The Most Heartbreaking And Inspirational Story Of The College Football Season, Is A Hoax

Longreads Pick

A college football star learns about the death of his grandmother and girlfriend on the same day and has inspirational stories written about him by major media outlets. But there’s a problem: His girlfriend never existed:

There was no Lennay Kekua. Lennay Kekua did not meet Manti Te’o after the Stanford game in 2009. Lennay Kekua did not attend Stanford. Lennay Kekua never visited Manti Te’o in Hawaii. Lennay Kekua was not in a car accident. Lennay Kekua did not talk to Manti Te’o every night on the telephone. She was not diagnosed with cancer, did not spend time in the hospital, did not engage in a lengthy battle with leukemia. She never had a bone marrow transplant. She was not released from the hospital on Sept. 10, nor did Brian Te’o congratulate her for this over the telephone. She did not insist that Manti Te’o play in the Michigan State or Michigan games, and did not request he send white flowers to her funeral. Her favorite color was not white. Her brother, Koa, did not inform Manti Te’o that she was dead. Koa did not exist. Her funeral did not take place in Carson, Calif., and her casket was not closed at 9 a.m. exactly. She was not laid to rest.

“Lennay Kekua’s last words to Manti Te’o were not ‘I love you.'”

Source: Deadspin
Published: Jan 16, 2013
Length: 15 minutes (3,763 words)

Jerry Seinfeld Intends to Die Standing Up

Longreads Pick

Joke-telling as a muscle:

“Since Richard Pryor, at least, confession has been prized in stand-up, and this is as true today as ever. The biggest stand-up story of 2012 came this summer, when the comedian Tig Notaro took a Los Angeles stage and wrung laughs from a saga of personal misery that included the sudden death of her 65-year-old mother followed by a breast-cancer diagnosis. At Seinfeld’s office, I asked him what he’d do, onstage, if he had a month like that, and I appended a ‘God forbid’ to the question. ‘Thank you for “God forbid,” ‘ he said. ‘I love it. Hilarious. You have to say that.’ He clapped his hands with delight. ‘If I had a month like that, I’d do a whole bit about “God forbid.” ‘”

Published: Dec 20, 2012
Length: 25 minutes (6,299 words)

You Owe Me

Longreads Pick

On teaching writing to children at a Houston cancer center. Featured in The Best American Essays 2012:

“The children I write with die, no matter how much I love them, no matter how creative they are, no matter how many poems they have written, or how much they want to live. They die of diseases with unpronounceable names, of rhabdomyosarcoma or pilocytic astrocytoma, of cancers rarely heard of in the world at large, of cancers that are often cured once, but then turn up again somewhere else: in their lungs, their stomachs, their sinuses, their bones, their brains. While undergoing their own treatments, my students watch one friend after another lose legs, cough up blood, and enter a hospital room they never come out of again.

“The M. D. Anderson Cancer Center in Houston, Texas, where I have taught poetry and prose for nearly ten years, is a world-renowned research institution. I have met the sickest children in the world there—children who have been treated already, somewhere else, and who have come for one last experimental treatment, who have one last chance at survival. In this capacity, my students often take part in studies. The treatments they receive are often groundbreaking, innovative ones that, with time, are perfected and standardized. This means their experiences, whether their disease is successfully eradicated or not, serve to build treatment protocols that eventually cure children throughout the world. But only a small percentage of the students I work with in the center’s classrooms live. Less than half, maybe less than a third, and I think less than that: I am just one of the writers in residence there. The numbers aren’t available to me.”

Published: Nov 25, 2012
Length: 22 minutes (5,637 words)

A group of young doctors from the Clinical Excellence Research Center at the Stanford School of Medicine are looking for new models to make health care better and more affordable:

Patel was second up in the presentation, a little nervous and barely tall enough to be seen behind the podium. She stated the problem in her target area: Cancer is the second-leading cause of death in the United States, with costs estimated to be $173 billion by 2020. These rising costs are unsustainable.

And what do many poor-prognosis cancer patients get for all the money spent? ‘Horrible treatment,’ she said, citing a statistic that silenced the room: Seventy-three percent of terminal cancer patients never have an end-of-life discussion with their oncologists. ‘Many patients are rushed off to chemotherapy without understanding the big picture. And when predictable treatment side effects happen at night and on weekends, patients who are unable to reach their oncologist end up in misery in emergency rooms and hospitals. Later in their illness, many die painfully in intensive-care facilities that bankrupt their families emotionally – and sometimes financially.’

During her presentation, Patel’s eyes became dark pools that threatened to overflow. A few people in the audience wept silently, perhaps remembering loved ones who had similarly suffered.

‘Overall, these added services improve the quality of life of patients, giving them what they need and want without delay,’ she added after describing her model. ‘And best of all, we lower health insurance costs … simply by doing the right thing.’

“Against the Odds.” — Kris Newby, Stanford Medicine

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