Posted inEditor's Pick

The Gene Machine: Building the Personal DNA Decoder

Have we mentioned the ifs? Like all potentially disruptive innovations, gene sequencers could fizzle. Their success depends on unpredictable events: how fast the technology improves, how quickly researchers can make medical discoveries based on the new machines and–most critically–whether drugs can be developed to treat diseases. Gene test prices could drop, becoming a low-margin commodity […]

Posted inEditor's Pick

The Truth Wears Off: Is There Something Wrong With the Scientific Method?

According to Ioannidis, the main problem is that too many researchers engage in what he calls “significance chasing,” or finding ways to interpret the data so that it passes the statistical test of significance—the ninety-five-per-cent boundary invented by Ronald Fisher. “The scientists are so eager to pass this magical test that they start playing around […]

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