“As vaccines roll out, the U.S. will face a choice about what to learn and what to forget.”
“The most precious resource the U.S. health-care system has in the struggle against COVID-19 isn’t some miracle drug. It’s the expertise of its health-care workers—and they are exhausted.”
“The coronavirus found, exploited, and widened every inequity that the U.S. had to offer.”
“The fight against the coronavirus won’t be over when the U.S. reopens. Here’s how the nation must prepare itself.”
“The U.S. may end up with the worst COVID-19 outbreak in the industrialized world. This is how it’s going to play out.”
The 14-year-old Achatinella apexfulva snail named George was the sole surviving member of its species. It was biologist David Sischo’s job to take care of George until it died, even as his team works to save other Hawaiian snails from extinction.
On the messy process that turned wolves into our domesticated companions — and why it is so hard to reconstruct it.
We asked a few writers and editors to choose some of their favorite stories of the year in specific categories. Here, the best in science writing.
Anti-malarial drugs are quickly becoming ineffective as Plasmodium parasites from western Cambodia evolve resistance to them. The writer travels to the Thai-Burmese border to interview a French researcher named François Nosten who is working to eliminate malaria before the resistant parasites spread to other countries:
Nosten thinks that without radical measures, resistance will spread to India and Bangladesh. Once that happens, it will be too late. Those countries are too big, too populous, too uneven in their health services to even dream about containing the resistant parasites. Once there, they will inevitably spread further. He thinks it will happen in three years, maybe four. “Look at the speed of change on this border. It’s exponential. It’s not going to take 10 or 15 years to reach Bangladesh. It’ll take just a few. We have to do something before it’s too late.”
Hundreds of scientists are developing innovative new ways of dealing with malaria, from potential vaccines to new drugs, genetically modified mosquitoes to lethal fungi. As Nosten sees it, none of these will be ready in time. The only way of stopping artemisinin resistance, he says, is to completely remove malaria from its cradle of resistance. “If you want to eliminate artemisinin resistance, you have to eliminate malaria,” says Nosten. Not control it, not contain it. Eliminate it.
In more than 3 billion years of existence on Earth, this merger happened once—and resulted in the complex life we have today:
There are many possible explanations, but one of these has recently gained a lot of ground. It tells of a prokaryote that somehow found its way inside another, and formed a lasting partnership with its host. This inner cell—a bacterium—abandoned its free-living existence and eventually transformed into the mitochondria. These internal power plants provided the host cell with a bonanza of energy, allowing it to evolve in new directions that other prokaryotes could never reach.
If this story is true, and there are still those who doubt it, then all eukaryotes—every flower and fungus, spider and sparrow, man and woman—descended from a sudden and breathtakingly improbable merger between two microbes. They were our great-great-great-great-…-great-grandparents, and by becoming one, they laid the groundwork for the life forms that seem to make our planet so special. The world as we see it (and the fact that we see it at all; eyes are a eukaryotic invention) was irrevocably changed by that fateful union—a union so unlikely that it very well might not have happened at all, leaving our world forever dominated by microbes, never to welcome sophisticated and amazing life like trees, mushrooms, caterpillars, and us.